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GLP-1s could be the missing pharmacological ally, reducing cravings across substances by hitting the brains universal reward hub

For retatrutide at 4,895 daltons, these comparisons suggest that nasal delivery is feasible but will require optimization, that brain delivery effects may be achievable at doses lower than needed for full systemic effect, and that absorption variability will be higher than with injection

Purpose-built for physicians Adults prescribed semaglutide may have increased risk for form of optic neuropathy Key takeaways: Adults prescribed semaglutide were more likely to develop nonarteritic anterior ischemic optic neuropathy than those using non-GLP-1 medications

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Children to manage