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If diarrhea persists beyond a few days at any dose level, it may indicate that the dose escalation happened too quickly

If you are at increased risk of B12 deficiency, supplements are one way to increase B12 intake after being approved by a medical professional

Long-Term, Supplemental, One-Carbon MetabolismRelated Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) Cohort. Journal of Clinical Oncology 35 (2017): 34403448

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