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Mitochondrial function naturally declines with age, and it is directly linked to reduced energy, slower metabolism, and increased susceptibility to age-related diseases

The transformation that seems impossible in month one becomes undeniable by month six

In a Phase 2 clinical trial published in the New England Journal of Medicine, participants receiving the highest dose lost an average of 24.2% of their body weight after 48 weeks

Other big (aka investable) companies in the GLP 1 race is: Amgen Amgen is developing MariTide , a monthly injectable, currently in Phase 3 trials

Conversely, other variables, such as disutility scores and complication costs, had moderate to minimal effects on the ICER