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The specific steps include drying the reaction solution and dissolving it in an appropriate amount of organic solvent (such as ether), adding an appropriate amount of silica gel, mixing evenly, and performing column chromatography separation

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Kiruthiga PV, et al

MMA can be treated with cobalamin injections on an individual basis, and long-term treatment includes the use of special formulas limiting the precursor substances of propionic acid (methionine-, valine-, threonine-, and isoleucine-free): high-calorie diets are provided to support growth and development, carnitine supplementation is recommended to promote organic acid excretion, and application of antibiotics can be used to reduce the intestinal flora