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Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials
Many people feel fatigued because they are mildly dehydrated and depleted in sodium, potassium, and magnesium, not because they need b12
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A vegan diet makes it more difficult to get enough minerals and nutrients like calcium, creatine, iron, K2, and B12 (also known as cobalamin) simply because they are usually found in animal products
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