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We collected and screened related articles published in or before June 2023 using PubMed, Google Scholar, and Web of Science

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Pharmacokinetics analysis in healthy men treated with CJC-1295 showed a dose-related increase in GH AUC regardless of whether the dose had been given only once or as multidoses

After quality control, we identified 47,413 cases of CAD (31,127 in men, 16,286 in women), 7961 cases of ischemic stroke (4915 in men, 3046 in women), 12,926 cases of heart failure (8456 in men, 4470 in women), and 18,382 cases of AF (12,260 in men, 6122 in women)