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i , Immunoblot of indicated proteins in HeLa cells treated with erastin (5 M) or indicated doses of KI696 (NRF2 activator) for 24 h

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A group of acidic residues coordinates two Mg 2+ to ATP and orienting the -phosphate group in the active site

The efficacy of N-acetylcysteine (an antioxidant and mucolytic agent) for patients with mild-to-moderate COPD is uncertain