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An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis

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When this pattern is observed consistently across multiple injections, copper sensitivity is the first thing evaluated and the primary reason protocols are adjusted or discontinued

Distinct from apoptosis, necrosis and autophagy, Dixon and coauthors proposed for the first time a new form of oxidation-dependent and iron-dependent cell death known as ferroptosis [19]