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Mitochondrial disease refers to a group of clinically heterogeneous disorders caused by dysfunction in the mitochondrial respiratory chain, often due to mutations in mitochondrial DNA (mtDNA) or nuclear DNA (nDNA) that encodes mitochondrial proteins

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Insomnia or Restlessness In some individuals, L-carnitine can cause a feeling of restlessness or trouble sleeping, particularly if taken in large doses or close to bedtime