NNMT as a metabolic enzyme, controls how cancer cells use energy and nutrients
On the antioxidant front, GHK-Cu increases superoxide dismutase (SOD) activity through copper cofactor delivery, elevates catalase activity for hydrogen peroxide breakdown, and increases total glutathione levels
Wrote the paper: CC, LL, and KL
Polyneuropathy typically presents gradually, beginning with paresthesia known as burning feet, followed by gait disturbances and variable muscle weakness in the lower limbs ( In the CNS, thiamine deficiency can lead to Wernickes encephalopathy, characterized by nystagmus, ophthalmoplegia, mental status changes, and unsteady stance and gait, due to apoptotic cell death in sensitive brain areas, mainly areas with high metabolic requirement, causing symmetrically distributed lesions among structures such as the third and fourth ventricles, besides dorsomedial thalamus (42)
Methylcobalamin is particularly effective in nerve health and regeneration, making it a preferred choice for B12 supplementation