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Scientific studies indicate that the prebiotic fermentation of FIBRULINE and FIBRULOSE chicory root fibres increase the absorption of calcium at 8g/day , through enhancement of the absorption capacity of the large intestine and contributes to an improvement of bone mineral density, which is linked to stronger bones

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J Clin Endocrinol Metab (2004) 89(6):305561

What clinicians have is extrapolation from copper metabolism physiology, Wilson disease pharmacology, and the known pharmacokinetics of other copper-containing compounds