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A Phase 2 trial of CX11, an investigational once-daily oral GLP-1 receptor agonist, reported up to 11.5% mean weight loss at 36 weeks, with weight loss continuing through the end of the study
& Johnson, H
Changing how and what you eat can often ease symptoms and reduce how hard your GI tract has to work
In fact, for many patients, microdosing is more effectivebecause it allows them to stay on the medication longer , build foundational health habits, and avoid the yo-yo cycle of starting and stopping due to side effects
More recently, a long-acting exendin-4-based analog bound to the Fc portion of immunoglobulin G (IgG) known as efpeglenatide is under clinical development, and would also be suitable for a once-weekly injection [8,9]
