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The distal end (S49 ECD ) of the helix was more mobile than the proximal one (E34 ECD ), which had an overall tendency to remain in the proximity of the TT-OAD2-binding site, driven by transient interactions with the ligand (Extended Data Table 1) and hydrogen bonds with the R299 ECL2 side chain (Extended Data Table 2)
In our latest deep, dive, we explore the intersection of Wegovy and Hashimoto's, shedding light on the role of this pioneering GLP-1 medication in weight management and its relevance for those wrestling with this common thyroid disorder
