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Nature PubMed Preclinical literature and narrative reviews describe pleiotropic actions including angiogenesis modulation (promotion in healing contexts and proposed inhibition in rodent corneal neovascularization models) and purported cytoprotective effects across diverse injury paradigms, but these remain unconfirmed in controlled human experiments
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doi: 10.1038/s41598-019-50044-z 69 ZhangQItagakiKHauserCJ
While some studies suggest a possible correlation between GLP-1 RAs and intestinal obstruction, others report no significant association, with discrepancies likely due to variations in study demographics, methodologies, and GLP-1 RA formulations
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