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10.1002/mnfr.202400227 35 KanwalF.KramerJ
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The agreement comes less than a year since Robert Michael took over as CEO of AbbVie and as the company looks for its next top-selling drugs following the loss of patent protection for its mega blockbuster autoimmune treatment Humira
This inhibition was evidenced by Oil Red O and AdipoRed staining, and by the downregulation of key adipogenic markers, including peroxisome proliferator-activated receptor gamma ( PPAR ), lipoprotein lipase ( LPL ), fatty acid-binding protein 4 ( FABP4 ), and CCAAT/enhancer-binding protein alpha ( C/EBP ) [12, 13, 22, 23]