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For example, a 12-week pilot study found no major changes in hirsutism, likely because the treatment duration was too short

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Methods Herein, we disclose a novel and efficient synthetic route to Semaglutide employing a rationally designed hexapeptide fragment, assembled via solid-phase peptide synthesis (SPPS) under carefully optimized conditions, which is subsequently introduced through fragment condensation at a late stage of the Semaglutide synthesis