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Before starting retatrutide (within a trial setting), your clinician should: Conduct a thorough medical history review , including assessment of conditions that may be trial exclusion criteria or require particular caution for example, a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2)

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Figure 7 Placebo-Controlled Studies With DPP-4 Inhibition as Add-on to Ongoing Metformin Therapy The DPP-4 inhibitors were also examined as add-on to on-going metformin in subjects with type 2 diabetes in 2426 week studies with a total number of 3,216 subjects [Table 2