High-fat meals delay gastric emptying independently of cagrilintide, so dosing before a high-fat dinner can compound the effect and increase nausea
Why is it choosing to do so now for people living with obesity a recognized, chronic medical condition that, like any other, requires appropriate treatment
Sudden, painless vision loss in one eye, blurred or distorted central vision, or any new visual symptom that appears quickly is a reason to call an eye doctor right away, not to wait and see
Toward More Tailored Dosing Strategies While the panacea of individualised dosing regimens might represent a leap too far in terms of complexity, the opportunity does exist for pharmaceutical companies to implement a more tailored approach when it comes to dosing, arriving at a more delicate balance of drug exposure, bioavailability, efficacy and safety based on the characteristics of certain patient cohorts
Back Holst, JJ (2022) 'Discovery of the GI effects of GLP-1: An historical perspective', Digestive Diseases and Sciences , 67, 2716-20