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[11] Any patient who becomes pregnant while on semaglutide should discontinue immediately and contact their obstetric provider
In particular, diabetes-related hyperglycemia acts through oxidative stress, fibrosis and severe inflammation in the reproductive tract, as demonstrated by the increase in serum transforming growth factor beta (TGF-), malonylaldehyde (MDA), and pentraxin-3 (PTX-3), with reduction in ovarian reserve and antimullerian hormone (AMH)
By slowing gastric emptying and enhancing the brains satiety response, GLP-1 medications may help the body and brain stay in sync
Increasing calories by 200-300 per day should slow loss to the 1-2 pound weekly range that optimizes the fat-to-muscle loss ratio
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