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In some cases, just one grapefruit or one glass of grapefruit juice is enough to limit the effectiveness of CYP3A4 2
(PubMed) Papandreou C, More M, Bellamine A
Alanine mutations confirmed that Trp221 and His223 at the surface groove are critical in the formation of the - glucan binding site on Dectin-1, and this site finds to be conserved among Dectin-1 of murine, chimpanzee, rhesus monkey, cow, and humans (168)
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ScienceDirect , PLoS ONE , vol
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