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It is wise to be especially cautious for patients who would be taking the highest dose, said Garcia-Webb
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Unlike traditional medications such as disulfiram, naltrexone, and buprenorphine, which primarily target neurotransmitter pathways directly associated with addiction, GLP-1RAs modulate reward mechanisms indirectly through metabolic and neuroendocrine pathways
Furthermore, the expression of sex hormone synthases CYP17A1 and StAR decreased, while that of CYP19A1 increased
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