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Retatrutide participants were losing approximately 1.7 lb per week during months 3 to 6, compared to roughly 1.2 lb per week for Tirzepatide and about 0.9 lb per week for Semaglutide during their respective fastest periods

Jin L, Jiang Q, Huang H, Zhou X (2024) Topical histone deacetylase inhibitor remetinostat improves IMQ-induced psoriatic dermatitis via suppressing dendritic cell maturation and keratinocyte differentiation and inflammation

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Treatment Duration and Expectations For optimal results, a minimum of 12 months on Tirzepatide or Semaglutide is recommended

An innate disposition for a healthier gut: GLP-1R signaling in intestinal epithelial lymphocytes