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A few years ago, this supplement was not available to the general public because the Food and Drug Administration did not approve of it for use on the skin

The chemistry and biological activities of N-acetylcysteine

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To improve the quality of the annotation, some authors [108, 127] designed a tailor-made annotation guideline or by using widely accepted corpora such as SMM4H and ADE-Corpus-V2 [33, 67]