Genomics 121 KondoC.SuzukiH.ItodaM.OzawaS.SawadaJ.KobayashiD.et al (2004)
IBATs approval for the treatment of PFIC has made the early diagnosis, supported by genetic screening, even more important both for paediatric and adult patients [16, 88] cases of patients successfully treated with IBATs, both in classic form and in rarer subtypes of PFIC [47, 53], even in the absence of a solid diagnosis of PFIC or in other cholestatic diseases, such as Alagille syndrome, have been described [92] supporting the primary role of clinical diagnosis
GHK is a tripeptide glycyl-L-histidyl-L-lysine isolated from human plasma in 1973 by Loren Pickart and Malcolm Thaler, who were investigating why serum from younger donors supported cultured liver cells better than serum from older donors
Gildea J, Xu P, Schiermeyer K, Yue W, Carey R, Jose P, Felder R