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Early on Holst found that the L-cells produced a peptide which contained the full glucagon sequence extended in both ends of the molecule
This includes patients who have problems related to the ileum which is the final section of the small intestine, such as Crohns disease
Giagulli VA, Carbone MD, Ramunni MI, Licchelli B, De Pergola G, Sabba C, et al
Kidney function has also been studied carefully
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