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This modulation is tentatively evidenced by a reported decrease in the expression of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interferon-gamma (IFN-), interleukin-1 beta (IL-1), and transforming growth factor-beta (TGF-), alongside chemokines like CCL2, CCL5, and CXCR4 following MGF experimentation

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Once constructed, the library could be easily screened with radioactive probes to identify specific genes It did not take long for Goodman to find the gene for somatostatin in his library (Bagley)

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Non-arteritic anterior ischemic optic neuropathy (NAION) is when blood and oxygen flow to the optic nerve is compromised, causing optic nerve swelling and sudden blindness in one eye, typically without any pain