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Nauck MA, Kind J, Kthe LDLD et al (2016) Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and patients with type 2 diabetes using exendin [9-39] as a GLP-1 receptor antagonist
(2015) 7:310ra167
Indeed, in physiological conditions, plasma GLP-1 has been suggested to increase not only after meals, but also in the pre-ingestive, cephalic phase, with its peak observed about an hour prior to meal initiation in rats [55]
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