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reported that unexplained liver injury in PCOS patients and animal models was accompanied by increased Fe deposition and downregulation of hepcidin and GPX4 expression in the liver, indicating the importance of iron metabolism in this type of unexplained liver injury (165)
Moreover, L-carnitine improves acetylcholine (neurotransmitter) levels in the brain, which may help improve memory, prevent neuronal aging, and treat weakness due to poor acetylcholine levels at the neuromuscular junctions in the body
Table S2
The tissue-specific effect of l-carnitine was found in many experiments in mammals or fish, in which the carnitine content of muscle was relatively stable, whereas the liver was more sensitive to carnitine supplementation or deficiency ( Reference Li, Li and Qin 32 , Reference Morand, Bouitbir and Felser 48 , Reference Wchter, Vogt and Kreis 49 )
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