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Patients should contact their healthcare provider if they experience severe or persistent symptoms that do not improve with conservative measures, persist despite an adequate 8-week trial of a PPI, or significantly impact quality of life

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These neurological biology studies have established Semaglutide as a research tool of broad CNS significance and contributed to the expanding neurological research programme investigating GLP-1R agonism in neurodegenerative and neuropsychiatric disease contexts

Fibromyalgia affects up to 3% of the general population and is a syndrome characterised by widespread pain, fatigue, sleep disturbances, and cognitive dysfunction, somatic symptoms, and psychiatric disorders [90]