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Furthermore, hMSC represent a heterogeneous population with cells derived from different tissue sources exhibiting different biological properties

Additional observations include shifts in enzyme activity, substrate utilization, and mitochondrial function, reflecting the broader influence of growth hormone axis activation

Male BALB/c-nu nude mice aged 4 weeks and weighing 18 ~ 22 g were purchased from the Experimental Animal Centre of Southern Medical University (Guangzhou, China) and housed in a specific pathogen-free air-conditioned room (25 2 and 65% 5% humidity) with a 12-h light/dark cycle

doi: 10.1016/j.molmet.2025.102094 43 BaggioLLDruckerDJ

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