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The landmark drug gained Food and Drug Administration (FDA) approval in 2005 under the brand name Byetta

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Patients should be advised to seek immediate medical attention if they experience severe or persistent gastrointestinal symptoms, signs of dehydration, inability to tolerate oral intake, severe constipation with abdominal distension, right upper quadrant pain with fever or jaundice, or symptoms suggestive of pancreatitis or bowel obstruction