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Coskun T et al.: LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss

GLP-1 use was compared to insulin/metformin or sodium-glucose cotransporter 2 (SGLT2) inhibitors in BC patients with T2D or glycated hemoglobin (HbA1c) 6.5% (T2D cohort), and to non-use in BC patients with obesity (obesity cohort)

The group receiving a 0.3 mg dose experienced a 6.0% weight loss, with 0.6 mg there was a 6.8% weight loss, with 1.2 mg there was a 9.1% weight loss, with 2.4 mg there was a 9.7% weight loss, and weigh 4.5 mg there was a 10.8% weight loss, compared with 3.0% weight loss for pooled placebo

GLP-1 analogues have proven utility in retarding diseases development in many animal and clinical trials, which are the potential and promising drugs to be utilized in AD, hypertension, and NASH

This peptide may alleviate pain, improve blood flow, and correct digestive disorders