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However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g
Lyophilization removes water, which slows many degradation pathways and makes the material easier to ship and store
While animal studies have shown promising results for tissue repair and anti-inflammatory effects, large-scale randomized controlled trials in humans are lacking
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