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10.1038/nrendo.2017.151 Summary Keywords tirzepatide, GLP-1/GIP dual receptor agonist, glycemic management, weight control, cardiovascular health management Citation Yang J, Gu Y, Chen H, Wang H, Hong L, Li B and Yang L (2024) Tirzepatides innovative applications in the management of type 2 diabetes and its future prospects in cardiovascular health

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Regulation of Nrf2-BDNF activation and expression is demonstrated by in vitro treatment of BV-2 cells with emodin and omega-3 docosapentaenoic acid, which promote BDNF expression, potentially through elevation of Nrf2 transcription (Liu et al., 2021

It may be related as much to the individual as to the medication

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