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J Biol Chem 1990
Downregulation or deficiency of pyruvate kinase leads to ATP depletion which in turn affects cell viability as well as accumulation of the glycolytic intermediates (2,3-diphosphoglycerate (2,3-DPG) that eventually leads to impaired glycolytic flux 46
Tmr oluumu engellendii gibi baklk sisteminde meydana gelmesi olas herhangi bir hastalkla mcadele edilebilmesi sz konusu olur
Is Tirzepatide a GLP-1
Despite early interest, it has not progressed through formal clinical development and remains a research compound
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