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It was previously approved by the FDA for diagnostic evaluation and treatment of pediatric GH deficiency and is now widely used off-label in research and clinical settings to address adult-onset GH insufficiency and age-related hormonal decline.

All embryos were cultured using sequential culture medium (Vitrolife, Gothenburg, Sweden) in incubators at 37C under 5% O 2 , 6% CO 2 , and 89% N 2 conditions with high moisture until day 6

The lower limit of PRR for the following HLT tumors was invariably greater than 1 in five models: thyroid neoplasms benign and malignant, pancreatic neoplasms malignant (excl islet cell and carcinoid), and islet cell neoplasms and APUDoma NEC (ICN&AN)

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Mayo, K.E., et al., 1995