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It is further theorized that these high calcium concentrations within the cell could prompt the secretory vesicles in the somatotroph cells to release growth hormone into the bloodstream
Patients should report if these symptoms worsen during rest or inactivity, improve with movement, and follow a pattern of being worse in the evening or nighttime hours
Hoegger MJ, Fischer AJ, McMenimen JD, Ostedgaard LS, Tucker AJ, Awadalla MA, Moninger TO, Michalski AS, Hoffman EA, Zabner J, et al
doi:10.1016/j.biopha.2021.111789
7A, B, Supplementary Fig
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