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Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways
While baseline liver ultrasonography was available for all participants, follow-up imaging assessments were not systematically performed, and hepatic outcomes were therefore primarily inferred from biochemical markers
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