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Control of the eIF4E activity: structural insights and pharmacological implications
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off-label in adolescents 12 to 17 HbA1c monitoring interval / every 3 months during dose titration Growth chart review / at every clinical visit (minimum every 3 months) Mental-health screening tool / PHQ-A (Patient Health Questionnaire, Adolescent) every 3 months Key metabolic labs at baseline / HbA1c, fasting glucose, lipid panel, LFTs, renal function, amylase/lipase Contraindication to flag / personal or family history of medullary thyroid carcinoma or MEN2 Injection site / abdomen, thigh, or upper arm
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