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From Pubchem Molecular Formula: C216H360N72O63S Molecular Weight: 5006 g/mol Sequence: YADAXFXNSYRKVLGQLSARKLLQDXMSRQQGQSNQRGARARL CAS number: 218949-48-5 PubChem CID: 56928011 As a GHRH analog, it binds to growth hormone releasing-hormone receptors in the anterior pituitary glands

In humans, thiamin deficiency caused by recessive mutations in the gene encoding THTR-1 leads to diabetes mellitus in the thiamin-responsive megaloblastic anemia syndrome (see Metabolic diseases below)

261 MR can enhance insulin-stimulated phosphorylation of AKT and S6 and activate PI3K/AKT signaling pathway

Human health effects of air pollution

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