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Lyubenova L et al

Late-response upregulated genes are strongly enriched in the ferroptosis pathway in an in vitro model of OA treated with fibronectin fragments (FN-f) (93)

The concentration of GSH is at high levels, and GSSG and ROS are at depressed levels to maintain redox homeostasis in cardiomyocytes

ROS production and associated inflammation are closely related to aging and numerous chronic diseases as diabetes, cardiovascular and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease