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for instance, case reports have demonstrated survival after a 25 g overdose [42] , and current guidelines in the United States and Canada indicate a high-risk ingestion to be ingestion of at least 30 g of APAP [43]
Blood levels often improve within a few months
This released glutamate is likely taken by astrocytes and accumulated in the form of glutamine, which can be provided to neurons, and a glutamateglutamine cycle rate increase is expected to result in stimulation of neuronal and astrocytic TCA cycle [105, 131]
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