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While not fully understood, the analgesic effects are believed to be due to the activation of the descending serotonergic inhibitory pathways in the central nervous system
Basically, the stomach muscles stop doing their job, slowing down the bodys ability to pass food through the digestive system
The medication also affects peristalsis, the wave-like muscle contractions that push food through your colon
Injection-site lumps that harden or keep growing rather than fading
53 Subsequently, Phase I experiments reported that the drug was well tolerated
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