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its lone pair electrons and larger atomic radius introduce structural distortions and spin density variations within the carbon lattice

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However, there is also a possibility that some of the effect may be independent of GLP-1, because DPP-4 inhibition still reduced -cell apoptosis in human islets cultured in the presence of exendin 9-39 (99), suggesting that other mediators might be involved, but it was also suggested that an anti-inflammatory action could have played a role (99)

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doi: 10.1038/s41575-018-0082-x 72

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