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The only active comparator ever used against cagrilintide monotherapy was liraglutide 3.0 mg in a Phase 2 study not tirzepatide so every ranking of the two is cross-trial inference across different populations and endpoints
Mechanisms of weight loss are multifactorial and independent of diabetes status, as seen in the SCALE Obesity and Prediabetes Study Group trial of GLP1RA in obese patients without diabetes, who lost 5.6 kg more weight than placebo (50)
Even mild cases may require close monitoring, respiratory support, and medications including antibiotics
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ArticlePubMed 68
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