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Why Researchers Study It Because insulin-like growth factor signaling plays a central role in cellular growth, protein synthesis, and tissue regeneration, researchers use IGF-1 LR3 as a tool to study these pathways under more sustained and observable conditions than native IGF-1 allows
Scoring of pro-inflammatory gene sets revealed no enrichment in Mg_A, modest enrichment in Mg_E, and strong enrichment in Mg_F, suggesting heterogeneous activation states across microglia subtypes found in MS (Supplementary Fig
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