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Synergistic Anti-Aging and Firming Benefits 1) Mechanism: - Copper ions synergize with the tripeptide to stimulate collagen I/III synthesis, improving skin firmness

Often included to reduce queasinessespecially during early treatment phases

Common combination options include: Vitamin C infusions for enhanced antioxidant effect Oral antioxidant supplements for maintenance Medical facials to improve skin hydration Sunscreen-based protection to preserve results Combining treatments allows for better skin resilience and more balanced results

Bergmann and Lane, 2003)

Although these mechanistic studies elucidate the catalytic role of key active site residues, the basis of substrate specificity for the nucleophilic amino acid in the plant GS is less well understood