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The 12mg cohort achieved the highest mean body weight reduction at -24.2% exceeding all published results for semaglutide (approximately -16% in the STEP trials) and tirzepatide (approximately -22.5% in SURMOUNT-1) at their respective maximum doses

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The lyophilized form demonstrates strong stability when stored correctly under standard laboratory conditions

For example, a gastrectomy, a surgical procedure where part of your stomach is removed, increases your risk of developing a vitamin B12 deficiency

This selective action has made it a significant area of research for metabolic disorders, particularly those related to obesity and fat metabolism, without the broader endocrine impacts associated with intact growth hormone