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The clinical difference is negligible
10.1016/j.pan.2018.08.001 Pancreatology
Tirzepatide (Mounjaro, Zepbound) is a long-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist with a prolonged elimination half-life of approximately 5 days (around 120 hours)
Mental health effects for weight-management indications (Saxenda, Wegovy), there have been reports of suicidal ideation and behaviour
Treatment with anticoagulation is highly effective when started promptly
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