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Common Side Effects of Vitamin B12 Injections Injection Site Reactions One of the most frequently reported side effects is a reaction at the injection site

Vegetarians, vegans, older adults, people with digestive disorders, and those on medications like metformin or acid reducers are more prone to low B12

Potential side effects can include hormonal imbalances, water retention, insulin resistance and joint pain

Research Use Disclaimer For research use only

Tried and tested: The Best Vitamin B12 Supplements, According to Dietitians Since B vitamins are found in many foods, you are most likely not at risk of developing a deficiency as long as you follow a well-rounded diet